Process of manufacturing the carbamic-acid ester of dichlorhydrin.



I. I, NoIlh-awing-.

BBU'NC BEOKMLNN, 9! BERLIN, GER-Em.

w! mmmm rim cannmxc-ncm names. or mcritcmmtin:

bajl'whom'z't may concern: a

Be it known, that I, Dr. BnUNo' Back- MANN, a subject of the German -Emperor, and residing at Belle-Alliance strasse 92,

Berlin, Germany, have invented certain new and useful Improvements in Processes of Manufacturing the Carbamic-Acid Ester of Dichlorhydrin, 'of which the following is a specification. This invention relates to 'aproces of manu'facturin the carbamic acid ester of di-- .chlorhydrm' which consists in causing "chlorid of carbamic acid to act on. a-d1- 'chlorhydrin. For example, 4 kg. carbamic acid-chlorid are slowly poured into 6.5 kg. a-di chlorhydrin while orously stirring ""and cooling the garbamateof di- 1 chlorhydrin is precipitated asafwhite solid substance. After sucking away theexcess offdichlorhydrin, washing with water and recrystallization; the carbamic acid esterof dichlorhydrin forms colorless needles havin a melting point of 8283 'C. he reaction takes place according to the following formula: cmcr omen 1- i L 0 ,+c|.oo.nn,'-7 +nc1' on 9.00am

H301 moi It is. true that Otto has published in the Jahrbuch fair Pralatz'scke Mediez'n, 1891,

a synthesis of the ester of 'dichlorisopropylcarbamic acid which, however, occupies-so much time and is so expensive that it cannot come into question as a commercial process. In addition, the product obtained according Specification of Letters intent. Applioatlonfllcd November 22,1913. Serial m. 802,537.

. bcin considerably superior to that o Patented Aug. 25, 1914.

scribed process. Thus Ottos product differs from that'made by the new process in' hyss ical. respects. Ottos product melts a 80 0., and that according-t0 the new process at 82-83 C. Further, Ottos product is tasteless, whereas that of the hereindescribed process has a bitter taste. Also, as regards solubility in water, the two products behave to Ottos synthesis differs in many respects .from that made according to thc'hereind'e 4c differently. 1 part of Ottos product dissolves in 65 parts of water, whereas 1- part of the product according to the hereindescribed process dissolves in 78 parts of water; Moreover, the ph siological action of the two products is di erent, the narcotic action of the product obtained by the new tprocess Ottos pro u'ct; comparative tests which have been made prove t at the narcotic actions of the products are a'proximately as 3:1, which shows the' excel ent therapeutic pro erty of What I claim is: v The hereindescribed process of manufac turing earbamic acidester of c-dichlorhydrin, consisting in subjectin or-dichlorhydrin, to ,the' action of car amic; acid chlorid.

In testimony whereof I aflix my signature in prrtsence of two witnesses.

, m. BRUNO BECKMANN.

Witnesses: I

*Womnmn HAUPT, HENRY Hearse.

00 the product made by. the herein escr ibed process. 

